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P. Nelson Le, MD, MBA

Chief Medical Officer

Greater Chicago Area · 1 connection

Spiras Health

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About

Pioneering healthcare executive who thrives at the intersection of clinical, business and technology and excels at developing innovative strategies and operations that drive value and growth while also dramatically improving member and associate experience. Skilled at deploying cutting-edge digital and AI solutions. Consistently applies data-driven approach to decision-making, winning trust and buy-in from other executives and teams by effectively communicating vision and driving consensus for Fortune 40, startup, health plan, and technology companies. High-Impact Results: @ Humana ➠Designed and lead the AI Program for Humana’s care delivery business, CenterWell, on target to deliver $200M+ run rate value at scale. ➠Improved core operations, growing pilot program membership 200%, team 100% & expanding budget to $7.4M. ➠Achieved consistent world class Care Management performance. ➠Developed joint use case to partner with a multinational e-commerce and cloud computing company in providing home health solutions. ➠Launched new platform, synchronizing data across all channels to enhance member experience. ➠Stood up Proactive Outreach and Testing programs to address COVID-19 pandemic. @

Experience

Chief Medical OfficerSpiras Health
Oct 2025
Associate Vice President, Portfolio Management, CenterWellHumana
Jan 2024 to Sep 2025
Associate Vice President, Clinical Strategy & AnalyticsHumana
Feb 2023 to Jan 2024
Associate Vice President, Care Model Experience and Integration, Care ManagementHumana
Mar 2022 to Feb 2023
Associate Vice President, Product Strategy, Digital Health and AnalyticsHumana
Oct 2020 to Mar 2022
Medical Director, Office of the Chief Medical OfficerHumana
Jul 2019 to Oct 2020
Medical Director & Vice President, Provider SolutionsAVIA
Jan 2016 to Jan 2019
Senior Clinical Advisor and Senior Product Advisor, Business DevelopmentInterSystems
Jan 2012 to Jan 2015
Vice President, Medical AffairsMcKesson Health IT
Jan 2010 to Jan 2012
Pediatric Transplant CardiologistChildren's Hospital Colorado
Jan 2006 to Jan 2007

Education

MIT Sloan School of Management
Master of Business Administration (MBA)
Boston University School of Medicine
Doctor of Medicine (MD) 7-Year Accelerated B.A.-M.D. Program
Oregon Health & Science University
Graduate Certificate in Biomedical Informatics
Children's Hospital of Philadelphia/University of Pennsylvania
Pediatric Cardiology
Yale-New Haven Children's Hospital
Pediatrics